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Target Audience: This activity was designed for healthcare professionals, including psychiatrists, neurologists, primary care physicians, clinical psychologists, pharmacists, psychotherapists, nurses, nurse practitioners, addiction counselors, social workers and others, who treat patients with psychiatric conditions.

Overview: This monograph is a summary of the bipolar disorder sessions previously presented at the 2007 NEI Psychopharmacology 2-Day Academies, with a discussion of the neurobiology, diagnosis, and treatment of bipolar spectrum disorders.

Learning Objectives: Upon completion of this activity, you should be able to:

• Track history and progression of symptoms and treatment responses for patients with mood/behavioral symptoms
• Select mood stabilizers and their doses based on patient presentation
• Use neurobiologic and mechanistic rationale when combining medications to treat bipolar spectrum disorders